By providing instruction on the rational use of oxygen and promoting it, negative repercussions can be avoided, such as loss of efficacy as a result of activities related to oxygen storage, distribution, and administration. Rational use of oxygen also involves controlling waste due to leaks in storage and distribution systems, use of gas at incorrect pressures, use of incorrectly adjusted flowmeters, and disconnections, among other problems.

85 potential therapeutic options are included within this database for COVID-19. This is the seventeenth edition and will continuously be updated as more research is released. The database is helpful for investigators, policy makers, and prescribers to ensure management of COVID-19 is based on the latest research.