Are liver and renal function tests required before prescribing paxlovid (nirmatrelvir/ritonavir)?

No, routine laboratory testing is not required. Routine testing may delay the administration of NMV/r, resulting in loss of its benefit against COVID-19. Providers may use their clinical judgment in patients with suspected renal or hepatic impairment, but the benefit of prescription outweighs the risk in patients without known impairment.